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Systemic infection and splenic abscess.

Aaron R Belknap1, Joseph Guileyardo1

  • 1Department of Pathology, Baylor University Medical Center at Dallas, Texas.

Proceedings (Baylor University. Medical Center)
|April 14, 2017
PubMed
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Splenic abscess, a rare complication of systemic infection, is difficult to diagnose due to nonspecific symptoms. This study highlights two autopsy cases of splenic abscess in patients with treatment-resistant sepsis, underscoring diagnostic challenges.

Area of Science:

  • Infectious Diseases
  • Abdominal Imaging
  • Surgical Pathology

Background:

  • Splenic abscess is an uncommon but serious complication of systemic infections.
  • It is often associated with infective endocarditis, posing diagnostic challenges due to nonspecific symptoms.

Observation:

  • Two cases of splenic abscess were identified post-mortem in patients presenting with treatment-resistant sepsis.
  • These cases underscore the difficulty in diagnosing splenic abscess, especially in critically ill patients.

Findings:

  • Abdominal computed tomography (CT) and ultrasound are typically diagnostic modalities for splenic abscess.
  • While antibiotic therapy is often insufficient, treatment may involve splenectomy or percutaneous drainage.

Implications:

Related Experiment Videos

  • The study emphasizes the importance of considering splenic abscess in the differential diagnosis of unexplained sepsis.
  • Improved diagnostic strategies and timely intervention are crucial for managing splenic abscess and improving patient outcomes.