[Long-term outcomes after cataract surgery in infants with congenital cataract]

J Y Qi1, W Xiao, M Y Wang

  • 1Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang110004, Liaoning Province, China.

Insights

Congenital cataract surgery in infants under 36 months, including intraocular lens (IOL) implantation, can lead to good visual acuity outcomes. Early IOL implantation before 24 months showed better results, with low rates of serious complications.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Visual Science

Background:

  • Congenital cataracts, affecting infants under 36 months, require timely surgical intervention.
  • Intraocular lens (IOL) implantation is a common procedure following cataract extraction in children.
  • Long-term outcomes and complication rates of early congenital cataract surgery are crucial for visual development.

Purpose of the Study:

  • To evaluate the long-term visual outcomes and complications of congenital cataract surgery performed before 36 months of age.
  • To determine the optimal timing for intraocular lens (IOL) implantation in relation to visual acuity.
  • To assess the impact of surgery timing on postoperative best corrected visual acuity (BCVA).

Main Methods:

  • A retrospective case study of 32 cases (57 eyes) of congenital cataract operated between January 2004 and January 2012.
  • All patients underwent cataract extraction with IOL implantation, posterior continuous curvilinear capsulorhexies, and anterior vitrectomy.
  • Long-term follow-up (up to 13 years) included best corrected visual acuity (BCVA) assessment and complication evaluation using statistical analyses like the Mann-Whitney U test.

Main Results:

  • Median age at cataract extraction was 6 months, and median IOL implantation age was 28 months, with a median follow-up of 67 months.
  • Postoperative BCVA was significantly better for surgeries performed between 2-4 months and for IOL implantation before 24 months.
  • Common complications included nystagmus (52.63%) and strabismus (29.82%), with posterior capsular opacity (8.77%) and glaucoma (3.51%) occurring less frequently.

Conclusions:

  • Congenital cataract surgery before 36 months with IOL implantation generally achieves good visual acuity.
  • Early IOL implantation (before 24 months) is associated with significantly better visual outcomes.
  • While complications like nystagmus and strabismus are observed, serious adverse events are infrequent.