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Detection of endolymphatic hydrops using traditional MR imaging sequences.
John H Keller1, Barry E Hirsch2, Ryan S Marovich2
1Department of Radiology, University of Pittsburgh Medical Center, United States.
American Journal of Otolaryngology
|April 18, 2017
Summary
Meniere
Area of Science:
- Otolaryngology
- Radiology
- Neuroscience
Background:
- Meniere's disease (MD) is a disorder of the inner ear.
- Accurate diagnosis of MD is crucial for effective management.
- Current diagnostic methods may have limitations.
Purpose of the Study:
- To investigate if Meniere's disease causes detectable changes in endolymphatic cavity size using MRI.
- To assess the utility of unenhanced high-resolution T2-weighted MRI in diagnosing MD.
Main Methods:
- A retrospective case-control study compared patients with MD to age- and sex-matched controls.
- High-resolution T2-weighted MRI of temporal bones was analyzed.
- Measurements included vestibule, utricle dimensions, and endolymphatic space width.
Main Results:
- Eighty-five case-control pairs were analyzed.
- Statistically significant differences in mean utricle area and area ratios were observed between MD patients and controls.
- No significant differences were found between affected and contralateral ears in MD patients.
Conclusions:
- Enlargement of the endolymphatic cavity in Meniere's disease is detectable with non-contrast T2-weighted MRI.
- This MRI technique can be a valuable diagnostic tool for MD.
- Intratympanic or delayed intravenous contrast may not be necessary for MD diagnosis.