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An approach to and web-based tool for infectious disease outbreak intervention analysis
Ashlynn R Daughton1, Nicholas Generous1, Reid Priedhorsky1
1Los Alamos National Laboratory, Los Alamos, 87544, USA.
Scientific Reports
|April 19, 2017
Summary
This study introduces a modified Susceptible-Infectious-Recovered (SIR) model for infectious disease control, incorporating parameter ranges and a web interface. It aims to improve outbreak trajectory estimation and decision-making in public health, enhancing collaboration between modelers and policymakers.
Area of Science:
- Epidemiology
- Mathematical Biology
- Public Health
Background:
- Infectious diseases pose a significant global health threat, leading to widespread mortality.
- Current infectious disease outbreak control relies on subjective surveillance and expert opinion, which are not always available.
- A gap exists between mathematical modeling and public health policy, hindering the development of practical decision-making tools.
Purpose of the Study:
- To develop a flexible and accessible modeling framework for infectious disease outbreak analysis.
- To bridge the gap between the infectious disease modeling community and public health decision-makers.
- To provide quantitative estimates of outbreak trajectories using available data.
Main Methods:
- Modified Susceptible-Infectious-Recovered (SIR) model incorporating disease control measures.
- Utilized parameter ranges instead of point estimates to reflect uncertainty.
- Developed a web user interface for broad accessibility and adoption.
- Applied the model to measles, norovirus, and influenza outbreaks.
Main Results:
- Demonstrated the feasibility of the modified SIR model for analyzing infectious disease outbreaks.
- The model provides quantitative estimates for outbreak trajectories, aiding in decision-making.
- The web interface facilitates broader use by public health professionals.
Conclusions:
- The developed SIR model with a web interface offers a practical tool for infectious disease outbreak management.
- Enhanced collaboration between modelers and public health officials is crucial for effective disease control.
- Further research is recommended to refine models and promote interdisciplinary interaction.