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DNA-spheres decorated with magnetic nanocomposites based on terminal transfer reactions for versatile target
Yingshu Guo1, Yujie Wang, Shuang Li
1Shandong Province Key Laboratory of Detection Technology for Tumor Makers, School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China. shushzhang@126.com.
Chemical Communications (Cambridge, England)
|April 19, 2017
Abstract:
We present an elegant approach to make a magnetic nanoparticle (MNP) conjugated DNA-sphere (MNP/DNA-SP) which is integrated with disulfide (MNP/DS-SP) or an aptamer (MNP/sgc8-SP) for GSH detection, selective cancer cell recognition, effective drug delivery, and bioimaging.