Quantitative depth-resolved microcirculation imaging with optical coherence tomography angiography (Part ΙΙ):...

Area of Science:

• Biomedical Optics
• Medical Imaging
• Microcirculation Imaging

Background:

• Optical Coherence Tomography (OCT) angiography is a key technology for non-invasive microcirculation imaging.
• Existing OCT angiography techniques face challenges in accurately visualizing microvascular networks.
• Understanding these phenomena is crucial for advancing diagnostic capabilities.

Purpose of the Study:

• To review phenomena explored in OCT angiography for microcirculation imaging.
• To emphasize processing algorithms developed to address OCT angiography limitations.
• To discuss quantitative parameters for clinical diagnosis and future OCT development.

Main Methods:

• Review of established and emerging OCT angiography techniques.
• Analysis of signal processing algorithms for microvascular imaging.
• Exploration of quantitative metrics for microvascular network characterization.

Main Results:

• Detailed examination of OCT angiography phenomena and their impact on microcirculation imaging.
• Identification of various processing algorithms and their effectiveness in overcoming imaging limitations.
• Discussion of depth-resolved microvascular parameters for potential clinical applications.

Conclusions:

• OCT angiography is a powerful tool for microcirculation imaging, with ongoing algorithmic advancements.
• Quantitative parameters derived from OCT angiography show promise for clinical diagnosis.
• Continued development in OCT technology is essential for enhanced microvascular visualization.