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Updated: Mar 4, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Should recent smoking be a contraindication for sleeve gastrectomy?
Ivy N Haskins1, Amy S Nowacki2, Zhamak Khorgami3
1Bariatric and Metabolic Institute, Department of Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Surgery, George Washington University, Washington, DC.
Sleeve gastrectomy is generally safe for smokers, but recent smokers face slightly higher risks of 30-day morbidity and mortality. Further research is needed to assess long-term benefits versus this initial perioperative risk.
Area of Science:
- Bariatric and metabolic surgery
- Cardiovascular health
- Surgical outcomes
Background:
- Bariatric surgery aims to reduce cardiovascular risks in obese patients.
- Smokers have higher cardiovascular event risks and may gain significant benefits from bariatric surgery.
- The safety of sleeve gastrectomy in smokers requires further characterization.
Purpose of the Study:
- To evaluate the independent impact of smoking on early postoperative complications and mortality following laparoscopic sleeve gastrectomy.
Main Methods:
- Utilized the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database.
- Analyzed data from 33,714 patients undergoing primary laparoscopic sleeve gastrectomy (2010-2014).
- Compared 30-day postoperative outcomes between smokers (smoked within one year pre-surgery) and nonsmokers.
Main Results:
- Smokers had a higher likelihood of unplanned reintubation (OR=1.88).
- Smokers experienced increased composite morbidity (4.3% vs. 3.7%), serious morbidity (0.9% vs. 0.6%), and 30-day mortality (0.2% vs. 0.1%).
- These risks persisted even after excluding patients with COPD, indicating a direct effect of smoking.
Conclusions:
- Laparoscopic sleeve gastrectomy is well-tolerated in both smokers and nonsmokers.
- Patients smoking within a year pre-surgery face a slightly elevated, though still low, risk of 30-day morbidity and mortality.
- Long-term benefits of improved comorbidities need to be weighed against this modest perioperative risk increase.
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