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Chapter 20 Gavi-Automated Vitrification Instrument.
Tammie K Roy1, Susanna Brandi2, Teija T Peura2
1, Genea Biomedx, Level 2, 321 Kent St, Sydney, NSW, Australia. tammie.roy@geneabiomedx.com.
Methods in Molecular Biology (Clifton, N.J.)
|April 20, 2017
Summary
Gavi automates oocyte and embryo cryopreservation by standardizing vitrification equilibration steps. This closed-system approach minimizes variability and reduces errors in laboratory and clinical settings.
Area of Science:
- Reproductive biology
- Cryobiology
- Biotechnology
Background:
- Cryopreservation of human oocytes and embryos is crucial for assisted reproductive technologies.
- Vitrification is a common cryopreservation method, but it is sensitive to procedural variability.
- Manual equilibration steps can introduce inconsistencies, potentially affecting outcomes.
Purpose of the Study:
- To introduce Gavi, an automated system for oocyte and embryo vitrification.
- To reduce variability in the equilibration process during cryopreservation.
- To enhance the standardization and repeatability of vitrification procedures.
Main Methods:
- Gavi automates the equilibration stages of the vitrification process.
- The system operates in a controlled, closed-system environment.
- It is designed for use with oocytes, cleavage-stage embryos, and blastocysts.
Main Results:
- Automated equilibration minimizes procedural variability.
- Reduces the potential for human error during vitrification.
- Ensures a standardized and repeatable cryopreservation procedure.
Conclusions:
- Gavi offers a standardized and reliable method for oocyte and embryo vitrification.
- The automated system enhances the safety and efficacy of cryopreservation.
- It is suitable for both laboratory and clinical applications in reproductive medicine.