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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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A Medication Reminder Mobile App: Does It Work for Different Age Ranges.

Mina Fallah1, Mobin Yasini2

  • 1School of Allied Medical Science, Tehran University of Medical Sciences, Tehran, Iran.

Studies in Health Technology and Informatics
|April 21, 2017
PubMed
Summary
This summary is machine-generated.

Developing a mobile medical app with user and health professional input improved medication adherence. This user-centered design approach enhances app usability and effectiveness for chronic disease self-management.

Keywords:
Mobile ApplicationsReminder SystemmHealthpatient adherence

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Area of Science:

  • Health Informatics
  • Mobile Health (mHealth)
  • Gerontology

Background:

  • Medication adherence is crucial for self-management in elderly patients with chronic diseases.
  • Medication reminder systems offer a potential solution to improve adherence rates.
  • Developing effective digital health tools requires user-centered design principles.

Purpose of the Study:

  • To design and evaluate an Android-based mobile medical application for medication reminders.
  • To assess the usability and efficacy of the developed mobile health application.
  • To explore the impact of involving end-users and healthcare professionals in app development.

Main Methods:

  • Two-phase study: application design followed by evaluation.
  • Hypothesized use case scenarios developed in collaboration with health professionals and patients.
  • Unified Modeling Language (UML) used for use case modeling.
  • Evaluation through usability and efficacy testing.

Main Results:

  • The mobile medical app was well-received by both younger individuals and older adults.
  • Usability and efficacy testing indicated positive user acceptance.
  • Collaborative design involving target users and health professionals positively influenced outcomes.

Conclusions:

  • Engaging end-users and healthcare professionals in the conception and development of health apps enhances usability and efficacy.
  • Mobile medical applications can be effective tools for improving medication adherence and self-management in chronic disease patients.
  • User-centered design is a critical factor for successful mHealth interventions.