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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
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Gastric Motility01:16

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Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
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Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

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Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
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Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives01:22

Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives

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Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This...
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Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

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Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
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Related Experiment Video

Updated: Mar 3, 2026

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
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Studying Murine Small Bowel Mechanosensing of Luminal Particulates

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Small Bowel Motility.

Carolina Malagelada1, Juan R Malagelada2

  • 1Digestive System Research Unit, University Hospital Vall d'Hebron; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd); Department of Medicine, Universitat Autònoma de Barcelona, 08035, Barcelona, Spain. cmalagelada@vhebron.net.

Current Gastroenterology Reports
|April 22, 2017
PubMed
Summary
This summary is machine-generated.

Diagnosing small bowel motility disorders is challenging due to complex measurement methods. This review covers current and emerging techniques for better characterization and treatment of these conditions.

Keywords:
Endoluminal image analysisIntestinal manometryIntestinal motilityMagnetic resonance imagingSmall bowel

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Area of Science:

  • Gastroenterology
  • Physiology
  • Medical Diagnostics

Background:

  • Small bowel motility disorders present with diverse symptoms, from functional complaints to severe malnutrition.
  • Accurate diagnosis is often difficult due to the complexity of measuring human intestinal contractile activity.

Purpose of the Study:

  • To review and critically evaluate current and emerging methodologies for diagnosing small bowel motility disorders.
  • To discuss how new diagnostic approaches can improve the characterization of motor function disturbances.

Main Methods:

  • Review of established techniques including conventional small bowel manometry, radiological methods, and intestinal transit tests.
  • Focus on novel methodologies: high-resolution manometry, magnetic resonance imaging, and endoluminal capsule image analysis.

Main Results:

  • Novel methods offer potential for less invasive and more accurate assessment of intestinal motor function.
  • Improved diagnostic capabilities are expected to enhance understanding of pathophysiological mechanisms.

Conclusions:

  • Advancements in diagnostic methodologies are crucial for better characterization of small bowel motility disorders.
  • Enhanced understanding facilitates more effective therapeutic strategies for patients.