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Updated: Mar 3, 2026

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Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
Published on: February 8, 2016
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A CASE OF AN AROMATASE-PRODUCING SERTOLI CELL TUMOR PRESENTING WITH GYNECOMASTIA
Hironori Daimon1, Yoshiaki Kinebuchi1, Hisanori Suzuki1
1Department of Urology, Shinonoi General Hospital.
Summary
A testicular Sertoli cell tumor caused gynecomastia by producing estradiol (E2). Surgical removal of the tumor normalized E2 levels and resolved the gynecomastia, with no signs of disease recurrence.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- A 64-year-old male presented with a left scrotal mass and bilateral gynecomastia.
- Initial tumor markers for germ cell tumors were within normal limits.
- Elevated serum estradiol (E2) levels were detected during endocrinological examination.

