Related Experiment Video
Updated: Mar 3, 2026
Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
Published on: September 1, 2022
Design and manufacturing challenges of optogenetic neural interfaces: a review
S B Goncalves1, J F Ribeiro1, A F Silva1
1CMEMS-UMinho, Department of Industrial Electronics, University of Minho, Guimaraes, Portugal.
None:
Optogenetics is a relatively new technology to achieve cell-type specific neuromodulation with millisecond-scale temporal precision. Optogenetic tools are being developed to address neuroscience challenges, and to improve the knowledge about brain networks, with the ultimate aim of catalyzing new treatments for brain disorders and diseases. To reach this ambitious goal the implementation of mature and reliable engineered tools is required. The success of optogenetics relies on optical tools that can deliver light into the neural tissue. Objective/Approach: Here, the design and manufacturing approaches available to the scientific community are reviewed, and current challenges to accomplish appropriate scalable, multimodal and wireless optical devices are discussed.
Significance:
Overall, this review aims at presenting a helpful guidance to the engineering and design of optical microsystems for optogenetic applications.
