A current affair: electrotherapy in wound healing.

Area of Science:

• Biomedical Engineering
• Regenerative Medicine
• Wound Healing Research

Background:

• The wound healing process involves complex cellular and biological mechanisms.
• The skin battery and current of injury are increasingly recognized for their role in chronic wound pathophysiology.
• Optimizing wound healing has significant socioeconomic benefits.

Purpose of the Study:

• To review the current understanding and application of electrical current in wound healing.
• To highlight the potential of electrostimulation therapy as a safe and effective treatment option.
• To emphasize the importance of translating research on electrical stimulation's biomolecular effects into clinical practice.

Main Methods:

• Literature review of studies on electrical stimulation in wound healing.
• Analysis of mechanisms underlying the effects of electrical current on cellular processes.
• Examination of clinical translation of electrostimulation therapies.

Main Results:

• Electrostimulation therapy shows promise as a treatment for accelerating wound healing.
• This therapeutic approach has demonstrated no device-related adverse effects.
• Understanding the biomolecular effects of electrical stimulation is key to its clinical application.

Conclusions:

• Applied electrical current, particularly electrostimulation therapy, is a viable and safe option for enhancing wound healing.
• Further research and clinical translation are needed to fully leverage the benefits of electrical stimulation for patients.
• Advancements in this field can significantly improve patient outcomes and quality of life.