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Magnetic Fields

Magnetic Fields

A moving charge or a current creates a magnetic field in the surrounding space, in addition to its electric field. The magnetic field exerts a force on any other moving charge or current that is present in the field. Like an electric field, the magnetic field is also a vector field. At any position, the direction of the magnetic field is defined as the direction in which the north pole of a compass needle points.
A magnetic field is defined by the force that a charged particle experiences...

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Updated: Mar 3, 2026

Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

Surface functionalized magnetic nanoparticles shift cell behavior with on/off magnetic fields.

Seongbeom Jeon¹, Ramesh Subbiah^1,2,3, Taufik Bonaedy^4,5

¹Department of Bionanotechnology, Gachon University, Seongnam, South Korea.

Journal of Cellular Physiology

|May 3, 2017

Summary

This summary is machine-generated.

Surface functionalized magnetic nanoparticles (MNPs) show improved biocompatibility and targeted intracellular delivery for drug delivery systems (DDS). These biocompatible MNPs offer potential for advanced imaging and cellular mechanics studies.

Keywords:

atomic force microscopy cell stiffness cytotoxicity interface magentic nanoparticles

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Last Updated: Mar 3, 2026

Biofunctionalization of Magnetic Nanomaterials

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Published on: July 16, 2020

Fabrication of Magnetic Platforms for Micron-Scale Organization of Interconnected Neurons

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Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

Area of Science:

Biomaterials Science
Nanotechnology
Materials Chemistry

Background:

Magnetic nanoparticles (MNPs) are promising for biomedical applications like contrast agents and targeted drug delivery systems (TDDS).
However, inherent MNP toxicity restricts their biological use.
Surface functionalization is key to enhancing MNP biocompatibility.

Purpose of the Study:

To prepare and characterize surface-functionalized MNPs with improved biocompatibility.
To evaluate the targeted intracellular delivery capabilities of these functionalized MNPs.
To investigate the impact of MNP uptake on fibroblast physico-mechanical properties.

Main Methods:

Co-precipitation, emulsification, and electro-spraying were used to synthesize iron oxide MNPs functionalized with poly(lactic-co-glycolic acid) (PLGA) and sodium alginate.
Nanoparticle characterization included size, surface charge, and morphological/structural analyses.
Biocompatibility and intracellular delivery efficiency were assessed, with delivery studies utilizing an applied magnetic field (H).

Main Results:

Synthesized nanoparticles were in the nanosize range with negative surface charges.
Morphological and structural analyses confirmed the nanostructure of the surface-functionalized NPs.
Functionalized MNPs demonstrated biocompatibility and enhanced, magnetically guided intracellular delivery.
Fibroblast mechanics were modulated by MNP uptake dependent on magnetic field application.

Conclusions:

Surface functionalization successfully improved MNP biocompatibility and targeting efficiency.
These biocompatible, surface-functionalized MNPs show significant potential for intracellular drug delivery, imaging, and cellular mechanics investigations.
The study highlights the tunable nature of MNP-cell interactions under magnetic control.