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Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
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The Ventricular-Arterial Coupling: From Basic Pathophysiology to Clinical Application in the Echocardiography

Francesco Antonini-Canterin1, Stefano Poli1,2, Olga Vriz3

  • 1Cardiologia Preventiva e Riabilitativa, Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy.

Journal of Cardiovascular Echography
|May 4, 2017
PubMed

Insights

Ventricular-arterial coupling, a measure of cardiovascular efficiency, links heart function and arterial system dynamics. This review explores its clinical applications in hypertension, heart failure, and other cardiovascular diseases.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Physiology

Background:

  • Ventricular-arterial coupling (VAC) describes the interaction between the heart's pumping ability and the arterial system's properties.
  • It reflects overall cardiovascular efficiency and can be quantified using metrics like arterial elastance (EA) and left ventricular end-systolic elastance (EES).

Purpose of the Study:

  • To review current literature on ventricular-arterial coupling.
  • To highlight the clinical utility of VAC assessment in various cardiovascular conditions.

Main Methods:

  • The review synthesizes findings from clinical studies evaluating VAC.
  • Focus is placed on the application of complex mathematical formulae, implementable via computerized algorithms, for noninvasive VAC calculation.

Main Results:

  • VAC assessment provides a comprehensive measure of global cardiovascular efficiency.
  • Noninvasive calculation methods facilitate clinical adoption of VAC indices.
  • Studies cover diverse scenarios including hypertension, heart failure, coronary artery disease, and valvular heart disease.

Conclusions:

  • Ventricular-arterial coupling is a valuable index for assessing cardiovascular efficiency.
  • Its noninvasive calculation enables widespread clinical application.
  • VAC analysis offers insights into various cardiovascular pathologies.

Keywords:
Echocardiographyhypertensionleft ventricular functionventricular-arterial coupling

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