Related Experiment Video
Updated: Mar 3, 2026

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models
Published on: December 8, 2023
Endoscopic Corneal Neurotization: Cadaver Feasibility Study.
Ilya Leyngold1, Christopher Weller1, Mark Leyngold2
1Division of Oculofacial Plastic and Reconstructive Surgery, Department of Ophthalmology, Duke University Hospital, Durham, North Carolina.
This study explored a minimally invasive technique for corneal neurotization using the supraorbital nerve. Endoscopic harvesting and transfer proved feasible in cadavers, offering a new approach for corneal nerve regeneration.
Area of Science:
- Ophthalmology
- Neurosurgery
- Surgical Innovation
Background:
- Corneal nerve damage can impair sensation and healing.
- Current treatments for corneal neuropathy have limitations.
- Restoring corneal innervation is a therapeutic goal.
Purpose of the Study:
- To assess the feasibility of a minimally invasive corneal neurotization technique.
- To investigate endoscopic harvesting of the supraorbital nerve for this purpose.
- To evaluate nerve transfer to the corneoscleral limbus.
Main Methods:
- A cadaver feasibility study was conducted.
- Endoscopic harvesting of the supraorbital nerve was performed.
- The nerve was transferred to the corneoscleral limbus.
Main Results:
- Successful endoscopic corneal neurotization was achieved in all cadaveric hemifaces.
- The technique demonstrated technical feasibility.
- The endoscopic approach facilitated minimally invasive access.
Conclusions:
- Endoscopic supraorbital nerve transfer is a feasible technique for corneal neurotization.
- This minimally invasive approach holds promise for restoring corneal sensation.
- Further research may explore clinical applications for corneal nerve regeneration.
More Related Videos
04:00Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
11:29Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011