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Posterior reversible encephalopathy syndrome(PRES).
Sreenivasa Rao Sudulagunta1, Mahesh Babu Sodalagunta2, Monica Kumbhat3
1Columbia Asia Hospital, Kirloskar Business Park, Hebbal, Bangalore, India.
Oxford Medical Case Reports
|May 6, 2017
Summary
Posterior reversible encephalopathy syndrome (PRES) is a brain condition often seen after massive blood transfusions. Early diagnosis and treatment are key to recovery and preventing complications.
Area of Science:
- Neurology
- Radiology
Background:
- Posterior reversible encephalopathy syndrome (PRES) is a neurological condition characterized by headache, seizures, altered mental status, and visual loss.
- It is defined by vasogenic edema in the white matter, predominantly affecting the posterior brain regions.
Observation:
- A 35-year-old female presented with seizures, urinary incontinence, and altered sensorium three hours after an unsafe abortion and massive blood transfusion.
- Brain MRI revealed T2/FLAIR hyperintensities in the bilateral occipital, parietal, and frontal cortex and subcortical white matter, consistent with PRES.
Findings:
- The patient's condition improved with intravenous fluids, antibiotics, antiepileptics, and blood pressure monitoring.
- PRES, particularly following massive blood transfusions, requires prompt recognition and management.
Implications:
- Early diagnosis and treatment of PRES can significantly reduce morbidity and mortality.
- This case highlights the importance of considering PRES in patients with neurological symptoms after massive blood transfusions.
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