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Updated: Mar 2, 2026

Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
Published on: August 6, 2012
A programmed terminal extension strategy to light up multiple beacons for DNA and cellular telomerase detection
Yucai Yang1, Chao Li, Xiaolu Hu
1Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P. R. China. ym.yin@hotmail.com.
Abstract:
Here we develop a new method for the sensitive detection of DNA and cellular telomerase using an enzyme-triggered terminal extension strategy that the produced strand can light up multiple beacons on the surface of gold nanoparticles.
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