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Updated: Mar 2, 2026
13:21
Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
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Lanthanide Complexes that Respond to Changes in Cyanide Concentration in Water
Jack D Routledge1, Xuejian Zhang1, Michael Connolly1
1Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QR, UK.
Angewandte Chemie (International Ed. in English)
|May 13, 2017
Summary
Lanthanide complexes with phenacylDO3A derivatives detect low cyanide concentrations in water through spectral changes, while DOTAM derivatives detect fluoride. These findings advance chemical sensing technologies.
Area of Science:
- Coordination Chemistry
- Analytical Chemistry
- Supramolecular Chemistry
Background:
- Lanthanide complexes are utilized in various sensing applications.
- Developing selective sensors for anions like cyanide and fluoride remains a challenge.
Purpose of the Study:
- To investigate the interaction of cyanide ions with lanthanide complexes of phenacylDO3A derivatives in aqueous solution.
- To explore the potential of these complexes as sensors for cyanide and fluoride ions.
Main Methods:
- Synthesis and characterization of lanthanide complexes with phenacylDO3A and DOTAM derivatives.
- Spectroscopic analysis (luminescence and NMR) to study ion interactions.
- Determination of binding affinities and detection limits for cyanide and fluoride.
Main Results:
- PhenacylDO3A-based lanthanide complexes showed spectral changes upon cyanide interaction due to cyanohydrin formation.
- These complexes detected cyanide at concentrations below 1 μm with minimal fluoride affinity.
- DOTAM-based lanthanide complexes did not interact with cyanide but responded to fluoride.
Conclusions:
- Lanthanide complexes of phenacylDO3A derivatives are effective and selective sensors for cyanide in aqueous media.
- Lanthanide complexes of DOTAM derivatives can be used for fluoride sensing.
- The study highlights the potential of tailored lanthanide complexes for specific anion detection.
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