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Published on: November 10, 2021
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Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd3+-loaded capsules with
Annah Farashishiko1, Sally E Plush, Karley B Maier
1Department of Chemistry, Portland State University, 1719 SW 10th Ave, Portland, OR 97201, USA. mark.woods@pdx.edu.
Abstract:
Nano-assembled capsules can incorporate large payloads of high relaxivity Gd3+, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd3+ relaxivities (70.7 s-1 mmolal-1).

