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Electrospinning Fibrous Polymer Scaffolds for Tissue Engineering and Cell Culture
Published on: October 21, 2009
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Recent advancements in electrospinning design for tissue engineering applications: A review
Alysha P Kishan1, Elizabeth M Cosgriff-Hernandez1
1Department of Biomedical Engineering, Texas A&M University, 5045 Emerging Technologies Building, 3120 TAMU, College Station, Texas, 77843-3120.
Journal of Biomedical Materials Research. Part A
|May 31, 2017
Summary
Electrospinning fabricates fibrous scaffolds for tissue engineering, mimicking the extracellular matrix. Recent advancements focus on tailoring scaffold architecture and properties to improve tissue regeneration and cellular responses.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Regenerative Medicine
Background:
- Electrospinning is a versatile technique for creating fibrous scaffolds.
- These scaffolds mimic the extracellular matrix structure.
- Material selection and fiber morphology can be tuned.
Purpose of the Study:
- To review advancements in electrospinning for tissue engineering.
- To highlight methods for modulating scaffold architecture.
- To summarize applications in enhancing tissue regeneration.
Main Methods:
- Overview of electrospinning processing variables.
- Discussion of setups for scaffold geometry control.
- Strategies for improving cellular infiltration and guidance.
Main Results:
- Electrospinning allows precise control over scaffold architecture.
- Advanced techniques enhance tissue property recapitulation.
- Improved cellular infiltration and guided behavior observed.
Conclusions:
- Electrospinning is a key technology for advanced tissue engineering scaffolds.
- Tailoring scaffold properties significantly impacts tissue regeneration.
- Further development promises enhanced clinical applications.
