Clinical examination for diagnosing circulatory shock
Bart Hiemstra1, Ruben J Eck, Frederik Keus
1Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Clinical examination alone is unreliable for estimating cardiac output (CO) in circulatory shock. Structured assessments combining multiple clinical signs significantly improve accuracy, offering a more reliable diagnostic approach.
Area of Science:
- Critical Care Medicine
- Cardiovascular Physiology
- Diagnostic Accuracy Studies
Background:
- Physicians rely on clinical examination and basic labs for circulatory shock diagnosis.
- Limited research exists on the diagnostic accuracy of clinical examination in shock.
- Circulatory shock is characterized by inadequate cardiac output (CO).
Purpose of the Study:
- To review the diagnostic accuracy of clinical examination in estimating CO in circulatory shock.
- To evaluate the effectiveness of single versus combined clinical signs for CO assessment.
Main Methods:
- Systematic review of recent studies on clinical examination for CO estimation.
- Analysis of univariable correlations between clinical signs and CO.
- Evaluation of diagnostic accuracy for both single signs and predefined clinical profiles.
Main Results:
- Single clinical signs (mottling, capillary refill time, temperature gradients) show poor correlation with CO.
- Physician's "educated guess" of CO based on unstructured examination has ~50% accuracy.
- Structured clinical profiles combining multiple signs achieve high accuracy (81-100%) for CO estimation.
Conclusions:
- Individual clinical signs are insufficient for estimating CO in shock.
- Unstructured clinical examination is unreliable for assessing CO.
- Structured clinical examination using combined signs offers superior accuracy and should be prioritized in clinical practice and future research.
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