Related Experiment Video
Updated: Mar 1, 2026

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
Published on: May 26, 2023
Toxic Effects of Nanostructured Silicon Dioxide on Multipotent Mesenchymal Stromal Cells
A P Lykov1,2, Yu A Lykova3, O V Poveshchenko4,5
1Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. aplykov2@mail.ru.
Abstract:
We studied the effect of nanostructured silicon dioxide particles on functional activity and ultrastructure of rat multipotent mesenchymal stem cells. A dose-dependent decrease in cell adhesion to plastics and their proliferative potential, accumulation of apoptotic cells, a decrease in the electron density of cell cytoplasm due to swelling and degenerative changes of organelles, and intracellular accumulation of nanostructured of silicon dioxide particles were observed.
More Related Videos
09:34Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
Published on: February 9, 2019
11:05Production and Administration of Therapeutic Mesenchymal Stem/Stromal Cell MSC Spheroids Primed in 3-D Cultures Under Xeno-free Conditions
Published on: March 18, 2017