Related Experiment Video

Updated: Mar 1, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

2.1K

Rationale for Percutaneous Intervention of CTO

Kethes C Waram1, Nicholas P Willis1, Sudhakar Girotra1

  • 1Department of Interventional Cardiology, Banner Good Samaritan Medical Center, 1111 East McDowell Road, Phoenix, AZ 85006, USA.

Interventional Cardiology Clinics
|June 6, 2017
PubMed

Insights

Percutaneous coronary intervention for chronic total occlusion can achieve over 90% success rates in experienced hands. Further randomized trials are needed to compare this intervention with optimal medical management.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • Chronic total occlusion (CTO) represents a significant challenge in coronary angiography, occurring in 15% of cases.
  • CTO lesions are frequently referred for surgical revascularization due to complexity.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of contemporary percutaneous coronary intervention (PCI) for CTO.
  • To identify barriers to the widespread adoption of advanced CTO PCI techniques.

Main Methods:

  • Review of contemporary strategies and techniques for CTO PCI.
  • Analysis of observational studies in carefully selected patient populations undergoing CTO PCI.

Main Results:

  • High success rates exceeding 90% are achievable with experienced operators.
  • Observational data suggest trends toward symptom relief, improved quality of life, left ventricular function, and mortality.
  • Improved tolerance to future ischemic events has been observed.

Conclusions:

  • Contemporary CTO PCI is a high-success-rate procedure when performed by experienced operators.
  • While observational data are promising, the lack of randomized controlled trials comparing CTO PCI with optimal medical management hinders its widespread adoption.

Keywords:
Chronic total occlusionClinical outcomeIndication for CTOMortalityMyocardial perfusion

More Related Videos

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

6.1K
Closure of a Patent Foramen Ovale PFO: An Intervention Sequence10:52

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence

Published on: December 23, 2022

6.4K

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
443
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
423
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
346
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
557
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
520
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
490