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Updated: Mar 3, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Transcatheter Aortic Valve Replacement for Severe Native Aortic Valve Regurgitation: A Multicenter and International
Sant Kumar1,2, Ashish Pershad2,3, David Elison4
1Department of Cardiology, Creighton University School of Medicine, Phoenix, Arizona, USA.
Abstract:
•Transcatheter aortic valve replacement for native aortic valve regurgitation is feasible but with modest technical success (79.8%).•Balloon-expandable valve use is linked to lower 30-day major adverse cardiac events versus self-expanding valve in high-risk patients.•Long-term outcomes driven by patient risk, not valve type.•Dedicated native aortic regurgitation systems still needed to improve procedural safety.
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