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Updated: Mar 1, 2026
06:04
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
658
Neurologic Events After Transcatheter Aortic Valve Replacement
Brandon M Jones1, E Murat Tuzcu1, Amar Krishnaswamy1
1Sones Cardiac Catheterization Laboratory, Department of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, Desk J2-3, Cleveland, OH 44195, USA.
Interventional Cardiology Clinics
|June 6, 2017
Summary
Transcatheter aortic valve replacement (TAVR) neurologic events are declining due to improved techniques and devices. Ongoing research aims to further reduce stroke risk, especially for broader patient groups undergoing TAVR.
Area of Science:
- Cardiovascular Medicine
- Neurology
- Medical Devices
Background:
- Transcatheter aortic valve replacement (TAVR) was initially associated with higher neurologic event rates than surgical AVR.
- Contemporary data indicate a downward trend in these events.
Purpose of the Study:
- To analyze the evolving risk of neurologic events following TAVR.
- To highlight current strategies and future directions for mitigating TAVR-related strokes.
Main Methods:
- Review of contemporary studies and clinical trials.
- Analysis of factors contributing to event reduction (patient selection, device evolution, operator experience).
Main Results:
- Neurologic event rates in TAVR are decreasing.
- Events are typically embolic and periprocedural, impacting morbidity and mortality.
- Advancements in embolic protection and antithrombotic therapies are key.
Conclusions:
- TAVR-related stroke incidence is improving.
- Further reductions are anticipated with ongoing technological and therapeutic advancements.
- Reducing stroke risk is crucial for expanding TAVR to lower-risk populations.
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