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Updated: Mar 1, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Acute Myocardial Infarction/Thrombectomy
Jonathan Soverow1, Manish A Parikh1
1Center for Interventional Vascular Therapy, Columbia-Presbyterian Hospital, 161 Fort Washington Avenue, Herbert Irving Pavilion, 6th Floor, New York, NY 10032, USA.
Insights
This review covers advanced techniques for complex acute myocardial infarction cases, discussing controversies in device use and nonculprit lesion treatment. Recent trials have influenced guideline shifts regarding support devices and thrombectomy.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
Background:
- Acute myocardial infarction (AMI) management involves complex decision-making, particularly in challenging cases.
- Evidence gaps and evolving clinical trial data necessitate nuanced approaches to treatment strategies.
Purpose of the Study:
- To review specialized techniques and devices for complex AMI cases.
- To discuss controversies and recent guideline shifts in device use and nonculprit lesion management.
Main Methods:
- Focused review of specialized techniques and devices in challenging AMI scenarios.
- Analysis of recent practice-changing clinical trials influencing guideline recommendations.
Main Results:
- Guidelines have shifted, downgrading routine use of assist devices in cardiogenic shock and aspiration thrombectomy.
- Consideration for nonculprit coronary intervention has been re-evaluated and revived.
Conclusions:
- Current evidence supports a more selective approach to mechanical circulatory support and thrombectomy in AMI.
- The management of nonculprit lesions in AMI requires careful consideration based on evolving trial data and patient-specific factors.
Abstract:
This article focuses on specialized techniques and devices used in the most challenging cases of acute myocardial infarction. Areas where high-quality evidence is either clear or absent are avoided. Controversies in the use of support or thrombectomy devices, the addition of adjunct pharmacology, and the decision to treat nonculprit lesions are discussed. Recent years have seen a shift in guidelines to downgrading the use of assist devices in cardiogenic shock and aspiration thrombectomy, whereas consideration of nonculprit coronary intervention has been revived. These changes come in the wake of a series of large, practice-changing clinical trials.
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