Related Experiment Video
Updated: Sep 12, 2026
Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
Published on: September 18, 2011
Acute Isolated Paraplegia Revealing an Ewing Sarcoma of the Thoracic Spine
Pierre-Aurélien Beuriat1, Sarah Melloul, Louise Galmiche
1Departments of *Pediatric Neurosurgery §Pathology, Necker-Enfants Malades Hospital, Paris Public Assistance Paris Hospital, (APHP), René Descartes University (Paris 5), Paris †Department of Pediatric Neurosurgery, Mother and children Hospital, Lyon ‡Centre for Cognitive Neuroscience, CNRS, UMR 5229, Bron, France.
Abstract:
Ewing sarcoma (ES) infrequently affects the spine. Diagnosis is usually made several weeks following growing symptoms. In this report, we present the case of a child with ES localized at the upper thoracic level. ES was revealed by isolated acute complete paraplegia mimicking medullary stroke. The girl was operated for decompressive laminectomy and tumor removal. Afterwards, she received adjuvant therapy. Subsequently, the child showed a slow improvement of her leg sensitivity associated with a partial motor recovery. ES can affect the mobile spine. Acute symptomatology due to intratumoral hemorrhage and sudden spinal cord compression may suggest the diagnosis. Neurological outcomes following ES are generally poor.
