Targeted cancer imaging and photothermal therapy via monosaccharide-imprinted gold nanorods
Danyang Yin1, Xinglin Li, Yanyan Ma
1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China. zhenliu@nju.edu.cn.
Chemical Communications (Cambridge, England)
|June 7, 2017
Abstract:
Plasmonic nanomaterials have been widely used for photothermal therapy (PTT) of cancer, but their recognition specificity remains challenging. We prepared monosaccharide-imprinted gold nanorods (AuNRs) for targeted cancer PTT, using sialic acid (SA) as a representative monosaccharide. The SA-imprinted AuNRs exhibited good specificity, enabling the killing of cancer cells without damaging healthy cells.
