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Celiac Crisis: A Rare Or Rarely Recognized Disease
Nadia Waheed1, Huma Arshad Cheema1, Hassan Suleman1
1Department of Hepatology & Nutrition, Children Hospital & Institute of child health, Lahore, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|June 7, 2017
Summary
Celiac crisis, a severe complication of celiac disease, presents with diarrhea and dehydration. Early diagnosis and treatment, including gluten-free diets, are crucial for recovery.
Area of Science:
- Pediatric Gastroenterology
- Clinical Medicine
Background:
- Celiac crisis is a rare, life-threatening complication of celiac disease.
- It is characterized by severe dehydration, metabolic disturbances, and neuromuscular weakness.
Purpose of the Study:
- To improve awareness and diagnosis of celiac crisis.
- To investigate risk factors, presentation patterns, and management strategies.
Main Methods:
- A descriptive cross-sectional study was conducted.
- Patients presenting with severe diarrhea, dehydration, and metabolic abnormalities, confirmed celiac disease, were enrolled.
Main Results:
- 126 patients were included, with a mean age of 5.25 years.
- Risk factors included poor social status, consanguinity, and early gluten introduction.
- Common symptoms were diarrhea, dehydration, and neuromuscular weakness; hypokalemia and metabolic acidosis were frequent biochemical abnormalities.
Conclusions:
- Celiac crisis is an under-recognized but common issue in developing countries.
- Neuromuscular paralysis and hypokalemia are key indicators.
- Gluten-free diets and supportive care are effective management strategies.
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