Orbital Involvement In Sinonasal Diseases

Area of Science:

• Otorhinolaryngology
• Ophthalmology
• Pathology

Background:

• Sinonasal diseases can extend to the orbit, leading to proptosis, ophthalmoplegia, and optic nerve damage.
• Orbital involvement signifies potentially aggressive sinonasal pathologies requiring careful management.

Purpose of the Study:

• To identify diagnoses in patients with co-existing sinonasal and orbital diseases.
• To analyze management strategies and outcomes for these complex cases.

Main Methods:

• Prospective study of 100 consecutive patients with orbital and sinonasal symptoms.
• Utilized CT/MRI scans and ophthalmological consultations.
• Final diagnoses confirmed by histopathology after excluding primary orbital pathologies.

Main Results:

• Allergic fungal rhinosinusitis (37%) and mucormycosis (17%) were the most frequent diagnoses.
• Proptosis was the most common orbital symptom (81 patients), followed by diplopia and ophthalmoplegia.
• Various other malignancies and rare pathologies were also identified.

Conclusions:

• Orbital involvement in sinonasal disease often indicates an aggressive pathology.
• Conditions like acute fulminant and chronic invasive fungal rhinosinusitis are particularly challenging to treat.