LARYNGEAL MUCORMYCOSIS IN AN UNCONTROLLED DIABETIC PATIENT: A CASE REPORT

Area of Science:

• Medical Mycology
• Infectious Diseases

Background:

• Mucormycosis, a rare fungal infection, is increasingly prevalent in immunocompromised individuals.
• Risk factors include diabetes, COVID-19-related immunosuppression, steroid use, and a rise in transplant and chemotherapy patients.
• While rhino-orbit-cerebral mucormycosis is common, other forms are emerging.

Observation:

• A 55-year-old male with poorly controlled diabetes presented with respiratory distress.
• The patient had no other identifiable risk factors for mucormycosis.
• An emergency tracheostomy was performed due to airway obstruction.

Findings:

• Laryngeal mucormycosis was diagnosed in the subglottic region via biopsies.
• Histopathological examination confirmed the presence of mucormycosis.
• The patient underwent debridement of necrotic tissue.

Implications:

• This case highlights the emergence of laryngeal mucormycosis, a rare presentation.
• Vigilant identification and control of predisposing factors are essential.
• Current guidelines recommend debridement and intravenous amphotericin B for treatment.