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Updated: Mar 1, 2026

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy
Published on: July 19, 2024
Bronchoscopic modalities to diagnose sarcoidosis
Sadia Benzaquen1, Alejandro Adolfo Aragaki-Nakahodo
1Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, University of Cincinnati, Ohio, USA.
Diagnosing sarcoidosis often requires bronchoscopic tissue samples. Endobronchial ultrasound transbronchial needle aspiration is favored for early stages, while cryobiopsy shows potential for difficult cases.
Area of Science:
- Pulmonology
- Respiratory Medicine
- Medical Diagnostics
Background:
- Sarcoidosis diagnosis can be challenging without clinicoradiographic evidence.
- Various bronchoscopic techniques exist for tissue acquisition in suspected sarcoidosis.
Purpose of the Study:
- To review recent evidence on bronchoscopic modalities for diagnosing sarcoidosis.
- To evaluate the utility of different techniques in obtaining tissue diagnosis.
Main Methods:
- Review of current literature on bronchoscopic diagnostic techniques for sarcoidosis.
- Analysis of evidence supporting endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA).
- Discussion of transbronchial lung cryobiopsy (TBCB) for sarcoidosis diagnosis.
Main Results:
- EBUS-TBNA is the preferred method for Scadding stages 1 and 2 sarcoidosis.
- TBCB is a newer technique with potential applications in sarcoidosis diagnosis.
- Limited data exists, but combining techniques improves diagnostic yield.
Conclusions:
- Bronchoscopic techniques are crucial when clinicoradiographic findings are insufficient for sarcoidosis diagnosis.
- A combination of bronchoscopic methods enhances the diagnostic success rate for suspected sarcoidosis.
- Further research is needed to fully elucidate the role of newer techniques like TBCB.
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