[Antibiotic stewardship : A programmatic approach to improved antimicrobial management]

Area of Science:

• Infectious Diseases
• Public Health
• Clinical Pharmacy

Background:

• Rising prevalence of multidrug-resistant gram-negative bacteria necessitates prudent antimicrobial drug use.
• German infection protection act (2011) mandates rational anti-infective use based on local resistance data.
• Antimicrobial stewardship (AMS) is a key strategy for improving bacterial infection treatment and adhering to regulations.

Purpose of the Study:

• To highlight the importance and implementation of AMS programs in clinical settings.
• To outline the objectives of AMS, including optimizing individual treatment and improving epidemiology.
• To emphasize the inclusion of all antimicrobial-using disciplines, including trauma surgery.

Main Methods:

• Implementation of multidisciplinary expert teams within hospitals.
• Development and monitoring of treatment standards for antimicrobial use.
• Establishment of regular consultations and ward rounds by AMS teams.

Main Results:

• AMS programs aim to optimize individual patient treatment outcomes.
• Longer-term goals include improving the overall epidemiological situation regarding antimicrobial resistance.
• AMS programs are relevant across all clinical disciplines, with specific considerations for trauma surgery.

Conclusions:

• AMS programs are essential tools for responsible antibiotic use in the face of rising antimicrobial resistance.
• Multidisciplinary collaboration and structured monitoring are key components of successful AMS implementation.
• Effective AMS strategies are vital for both individual patient care and public health in combating resistant infections.