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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

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Updated: Feb 28, 2026

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes

Evaluation of Cardiac Contractility Modulation Therapy in 2D Human Stem Cell-Derived Cardiomyocytes

Published on: December 16, 2022

From D2B to B2D: Value based STEMI care!

Joseph Ebinger¹, Timothy D Henry¹

¹Cedars-Sinai Heart Institute, Los Angeles, California.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions

|June 15, 2017

Summary

This summary is machine-generated.

The CADILLIAC Risk Score helps identify patients with ST-elevation myocardial infarction (STEMI) who can be safely discharged early after percutaneous coronary intervention (PCI). This approach may enhance care quality and reduce costs.

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Area of Science:

Cardiology
Health Economics

Background:

ST-elevation myocardial infarction (STEMI) management involves percutaneous coronary intervention (PCI).
Early discharge strategies are being explored to optimize patient care and resource utilization.

Discussion:

The CADILLIAC Risk Score demonstrates accuracy in identifying STEMI patients suitable for early discharge post-PCI.
Early discharge post-PCI for STEMI has the potential to improve care quality and decrease healthcare costs.

Key Insights:

The CADILLIAC Risk Score is a validated tool for safe early discharge in STEMI patients undergoing PCI.
Implementing early discharge can lead to significant cost savings and improved patient outcomes.

Outlook:

Prospective validation of the CADILLIAC Risk Score is recommended.
Formal cost-effectiveness analyses are needed to support widespread adoption of this early discharge strategy.