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Peripheral T-lymphocyte counts in seborrhoeic keratosis
1Department of Dermatovenereology, Govt.Medical College & Rajendra Hospital, Patiala - 147001, Punjab, India.
Indian Journal of Dermatology, Venereology and Leprology
|June 16, 2017
Summary
Seborrhoeic keratosis and stucco keratosis show increased T-lymphocyte counts, indicating a significant role for cell-mediated immunity in these skin conditions. This finding highlights the immune system
Area of Science:
- Dermatology
- Immunology
Background:
- Seborrhoeic keratosis and stucco keratosis are common skin conditions.
- The role of cell-mediated immunity in these conditions requires further investigation.
Purpose of the Study:
- To investigate the T-lymphocyte counts in patients with clinically diagnosed seborrhoeic keratosis and stucco keratosis.
- To determine the association between T-lymphocyte levels and these skin conditions.
Main Methods:
- Histopathological confirmation of 148 cases of seborrhoeic keratosis and 12 cases of stucco keratosis.
- Peripheral T-lymphocyte counts were determined using Thomson's E-rosette method (1977).
Main Results:
- Histopathology confirmed 123 cases of seborrhoeic keratosis and 8 cases of stucco keratosis.
- Peripheral T-lymphocyte counts were statistically significantly increased in both seborrhoeic keratosis and stucco keratosis patients.
- The findings suggest a significant role for cell-mediated immunity in seborrhoeic keratosis.
Conclusions:
- Cell-mediated immunity plays a significant role in the pathogenesis of seborrhoeic keratosis.
- Increased T-lymphocyte counts are observed in both seborrhoeic keratosis and stucco keratosis.
