Related Experiment Video
Updated: Feb 28, 2026

Fast Grid Preparation for Time-Resolved Cryo-Electron Microscopy
Published on: November 6, 2021
Time-resolved cryo-electron microscopy: Recent progress
1Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, 650 W. 168th Street, New York, NY 10032, United States; Department of Biological Sciences, Columbia University, United States.
Abstract:
Time-resolved cryo-electron microscopy (cryo-EM) combines the known advantages of single-particle cryo-EM in visualizing molecular structure with the ability to dissect the time progress of a reaction between molecules in vitro. Here some of the recent progress of this methodology and its first biological applications are outlined.
Related Concept Videos
Cryo-electron Microscopy
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

