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Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
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Polymeric nanoparticles: Promising platform for drug delivery.
Khalid M El-Say1, Hossam S El-Sawy2
1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
International Journal of Pharmaceutics
|June 21, 2017
Summary
Polymeric nanoparticles represent a significant advancement in nanomedicine for drug delivery. These nano-sized particles effectively transport therapeutics to target sites, overcoming challenges like oral delivery and blood-brain barrier penetration.
Area of Science:
- Nanomedicine
- Materials Science
- Pharmacology
Background:
- Nanomedicine has revolutionized drug delivery, aiming to improve therapeutic efficacy and overcome drug limitations.
- Particulate-based nanocarriers have shown significant promise in targeted drug delivery applications.
Purpose of the Study:
- To review the design, fabrication, and successful applications of polymeric nanoparticles in drug delivery.
- To highlight the ability of polymeric nanoparticles to address challenges in therapeutic administration.
Main Methods:
- Review of existing literature on polymeric nanoparticle synthesis and characterization.
- Analysis of case studies demonstrating the efficacy of polymeric nanoparticles in overcoming delivery barriers.
Main Results:
- Polymeric nanoparticles offer versatile platforms for encapsulating and delivering various therapeutic agents.
- Successful strategies have been developed for using these nanoparticles to enhance oral peptide delivery.
- Polymeric nanoparticles have demonstrated efficacy in facilitating drug passage across the blood-brain barrier.
Conclusions:
- Polymeric nanoparticles are a key innovation in nanomedicine, enabling targeted and effective drug delivery.
- Their unique properties allow for overcoming significant pharmacokinetic and pharmacodynamic challenges.
- Further development of polymeric nanoparticles holds great potential for future therapeutic interventions.
Keywords:
Cancer therapyCentral nervous systemGene deliveryOral bioavailabilityPolymeric nanoparticlesMore Related Videos
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