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Published on: March 10, 2023
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Liver transplantation for hepatocellular carcinoma
Jennifer Berumen1, Alan Hemming2
1Department of Surgery, University of California, San Diego, 9300 Campus Point Dr, MC 7745, La Jolla, CA, 92037, USA. jberumen@gmail.com.
Abdominal Radiology (New York)
|June 22, 2017
Summary
Liver transplantation is a key treatment for hepatocellular carcinoma (HCC), with established criteria ensuring good outcomes. Alternative therapies and technical aspects, including living donor options, are also explored for HCC management.
Area of Science:
- Hepatobiliary Surgery
- Transplant Surgery
- Surgical Oncology
Background:
- Hepatocellular carcinoma (HCC) management has advanced significantly.
- Liver transplantation is increasingly utilized for HCC treatment.
- Established criteria aim for transplant survival rates comparable to other indications.
Purpose of the Study:
- To review current criteria for liver transplantation in HCC patients.
- To discuss alternative treatment options for HCC.
- To highlight technical considerations in liver transplantation for HCC.
Main Methods:
- Review of established criteria for liver transplantation in HCC.
- Discussion of surgical resection as an alternative.
- Exploration of downstaging techniques for HCC.
- Consideration of living donor liver transplantation.
Main Results:
- Liver transplantation offers acceptable outcomes for selected HCC patients.
- Survival rates after liver transplantation for HCC are comparable to other transplant indications.
- Alternative treatments and technical aspects are crucial for comprehensive HCC management.
Conclusions:
- Liver transplantation is a viable and effective treatment for HCC within specific criteria.
- Surgical resection and downstaging represent important alternative or adjunctive therapies.
- Technical aspects and donor options, including living donors, are vital considerations in liver transplantation for HCC.

