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Exosomes: From Cell Debris to Potential Biomarkers in Transplantation

Adrian E Morelli1

  • 11 Thomas E Starzl Transplantation Institute, Pittsburgh, PA. 2 Departments of Surgery and Immunology, University of Pittsburgh, Pittsburgh, PA.

Transplantation
|June 23, 2017
PubMed
Abstract

No abstract available in PubMed .

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Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
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