Injectable scaffolds: Preparation and application in dental and craniofacial regeneration

Area of Science:

• Biomaterials Science
• Regenerative Medicine
• Dental and Craniofacial Research

Background:

• Injectable scaffolds present significant advantages over pre-formed scaffolds for tissue regeneration applications.
• The field of injectable scaffolding is rapidly advancing, offering new possibilities for clinical translation.

Purpose of the Study:

• To provide a comprehensive review of injectable scaffolds for dental and craniofacial tissue regeneration.
• To discuss the materials, characteristics, and applications of these advanced biomaterials.

Main Methods:

• Literature review of injectable scaffolding systems.
• Analysis of natural, synthetic, and composite biomaterials.
• Summary of applications in dental and craniofacial tissue regeneration.

Main Results:

• Overview of injectable scaffolding materials, including natural, synthetic, and composite types.
• Discussion of characteristic parameters and gelation mechanisms.
• Illustration of advanced injectable scaffolding systems and their applications.

Conclusions:

• Injectable scaffolds show great promise for regenerating dental and craniofacial tissues.
• Further research and development are needed to optimize these systems for clinical use.
• This review provides a roadmap for future advancements in the field.