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Glomangiomatosis: a case report.

Valerie A Fitzhugh¹, Kathleen S Beebe², Cornelia Wenokor³

¹Department of Pathology and Laboratory Medicine, Rutgers, the State University of New Jersey-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA. fitzhuva@njms.rutgers.edu.

Skeletal Radiology

|June 29, 2017

Summary

This summary is machine-generated.

Multiple glomangiomatosis, a rare glomus tumor variant, presents as multiple, painful leg masses in young adults. This case highlights the diagnostic challenges and the importance of biopsy for accurate identification.

Keywords:

Glomangiomatosis Glomus tumor Magnetic resonance imaging Perivascular tumors

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Area of Science:

Vascular Tumors
Dermatopathology
Medical Imaging

Background:

Glomangiomatosis is a rare, benign vascular tumor, a variant of glomus tumors, accounting for a small percentage of these lesions.
Typically presents as multiple, deep, extensive, and painful lesions, often on distal extremities.
These tumors arise from small arteriovenous anastomoses and are frequently observed in young adults.

Observation:

A 33-year-old male presented with multiple, slow-growing leg masses over five years, one causing significant pain.
One lesion was noted to be congenital, present since birth.
Initial imaging suggested neurofibromatosis, indicating potential diagnostic complexity.

Findings:

Biopsies from multiple lesions confirmed the diagnosis of multiple glomangiomatosis.
The case underscores the atypical presentation and diagnostic considerations for this rare vascular tumor.
Glomangiomatosis can exhibit recurrence, necessitating long-term monitoring.

Implications:

Accurate diagnosis of glomangiomatosis is crucial for appropriate management and patient counseling.
Distinguishing glomangiomatosis from other vascular lesions and tumors is essential.
Further research into the pathogenesis and optimal treatment strategies for glomangiomatosis is warranted.