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Recurrent Optic Nerve Pilocytic Astrocytoma: A Rare Case
Sudha Girish Menon1, Vuppalapati Nishant Janardhana Raju2, Sulatha V Bhandary3
1Assistant Professor, Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.
Journal of Clinical and Diagnostic Research : JCDR
|June 30, 2017
Summary
This case study details a rare instance of recurrent pilocytic astrocytoma in the optic nerve of a 40-year-old male without Neurofibromatosis Type I. The study highlights the challenges in managing this low-grade glioma
Area of Science:
- Neuro-oncology
- Ophthalmology
- Pediatric Neurosurgery
Background:
- Pilocytic astrocytoma is a common low-grade glioma in children and young adults.
- Optic nerve pilocytic astrocytoma is a subtype often linked to Neurofibromatosis Type I.
- Recurrence can occur, necessitating long-term surveillance.
Observation:
- A 40-year-old male presented with proptosis and exposure keratopathy.
- MRI revealed an optic nerve mass extending to the chiasm.
- The patient had two prior surgeries for optic nerve pilocytic astrocytoma.
Findings:
- Histopathology confirmed pilocytic astrocytoma (WHO Grade I).
- The patient had no history or signs of Neurofibromatosis Type I.
- This represents an unusual case of recurrent pilocytic astrocytoma without NFI.
Implications:
- Recurrent pilocytic astrocytoma can occur even without NFI.
- Optic nerve gliomas require vigilant long-term follow-up.
- Management strategies may need to be individualized for non-NFI associated recurrent cases.
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