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The HoneyComb Paradigm for Research on Collective Human Behavior

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Published on: January 19, 2019

Factors Influencing IACUC Decision Making: Who Leads the Discussions?

Jerald Silverman¹, Charles W Lidz^1,2, Jonathan Clayfield²

¹1 UMass Medical School, Worcester, MA, USA.

Journal of Empirical Research on Human Research Ethics : JERHRE

|June 30, 2017

Summary

Scientists may significantly influence Institutional Animal Care and Use Committee (IACUC) decisions. Analysis of 87 protocol reviews revealed scientists presented the most protocols and topic mentions during discussions.

Keywords:

IACUCs federal regulations qualitative methods research ethics research review

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Area of Science:

Animal research ethics
Scientific governance

Background:

Institutional Animal Care and Use Committees (IACUCs) are central to decisions regarding animal research.
Concerns exist regarding the extent of influence scientists hold within IACUC decision-making processes.

Purpose of the Study:

To investigate potential dominance in IACUC discussions by analyzing participant contributions.
To assess the influence of different member groups on IACUC protocol reviews.

Main Methods:

Analysis of audio recordings from 87 protocol reviews across 10 IACUCs.
Coding of discussion topics to quantify participant contributions.
Comparison of topic mentions per participant group.

Main Results:

Animal research scientists contributed the highest total number of topic mentions.
On a per-person basis, chairpersons and attending veterinarians made the most mentions.
Discussion topics frequently mirrored those presented by scientists in their protocols.

Conclusions:

The significant number of protocols presented by scientists and their extensive discussion contributions suggest a substantial influence on IACUC decision-making.
Findings highlight the need for continued examination of group dynamics within IACUCs to ensure balanced ethical oversight.