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Updated: Feb 27, 2026

Author Spotlight: Introducing the Tile/SED/Array Interface for Rapid Field of View Positioning in Tissue Imaging
Published on: September 15, 2023
From Image Tiles to Web-Based Interactive Measurements in One Stop
Antoine Vandecreme1, Michael Majurski1, Joe Chalfoun1
1Information Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD.
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This article introduces readers to a web-based solution useful for interactive nanoscale measurements of centimeter-sized specimens. This solution is a client-server system that promotes collaborative measurements and discovery. The system consists of multiple computational modules that enable uploading microscopy images, extracting metadata, assembling many nanometer-resolution images into an image covering a centimeter-sized area, and interactive viewing and measuring of objects of interest at multiple length scales over terabyte-sized images. We illustrate the use of the system on images of aerosolized nanoparticles and dye particles on printing paper.

