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Updated: Feb 26, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Bone Margin Analysis for Osteonecrosis and Osteomyelitis of the Jaws
Mohammed Qaisi1, Lindsay Montague2
1Division of Oral & Maxillofacial Surgery, John H. Stroger, Jr. Hospital of Cook County, 1900 West Polk Street, Suite 612, Chicago, IL 60612, USA; Division of Otolaryngology, John H. Stroger, Jr. Hospital of Cook County, 1900 West Polk Street, Suite 612, Chicago, IL 60612, USA.
Abstract:
Bone margin analysis in cases of osteomyelitis, osteoradionecrosis, and medication-related osteonecrosis of the jaw is a controversial topic. There is little evidence to guide treatment and the interpretation of bone margin results. This article examines the significance of margin status and any possible effect on progression of the disease process. A review of various treatment adjuncts used for intraoperative margin analysis during removal of affected tissue is provided. Literature on the role of imaging is also discussed with regards to treatment planning for surgical resection. The histology of the three separate entities including the approach to surgical and pathologic evaluation of margins is also discussed.
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