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Updated: Feb 26, 2026

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Applications of Dual-Energy Computed Tomography for the Evaluation of Head and Neck Squamous Cell Carcinoma
Reza Forghani1, Hillary R Kelly2, Hugh D Curtin3
1Department of Radiology, Segal Cancer Centre and Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Room C-212.1, 3755 Cote Sainte-Catherine Road, Montreal, Quebec H3T 1E2, Canada.
Abstract:
There are multiple emerging applications of dual-energy computed tomography (DECT) for the evaluation of pathology in the head and neck, in particular head and neck squamous cell carcinoma. Studies suggest that DECT image sets reconstructed as supplements to routine diagnostic images may improve lesion visualization, determination of tumor extent, and identification of invasion of critical anatomic structures. This article reviews the evidence for the use and potential advantages of supplementary DECT reconstructions for the evaluation of head and neck squamous cell carcinoma. A summary of potentially useful reconstructions and a suggested approach for multiparametric DECT evaluation of head and neck cancer based on current evidence are presented.
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