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Implementing Clinical Prediction Models: Pushing the Needle Towards Precision Pharmacotherapy
S R Dorajoo1,2, A Chan1,3,4
1Department of Pharmacy, National University of Singapore, Singapore.
Clinical Pharmacology and Therapeutics
|July 20, 2017
Summary
Clinical prediction models offer precision drug therapy but face implementation barriers. Ethical and regulatory hurdles must be addressed for precision pharmacotherapy to advance.
Area of Science:
- Pharmacotherapy
- Clinical Prediction Models
- Precision Medicine
Background:
- Clinical prediction models offer potential for precision drug therapy.
- Widespread adoption of these models in practice remains limited.
- Existing barriers to implementation are well-documented.
Purpose of the Study:
- To discuss less recognized barriers hindering the implementation of clinical prediction models for precision prescribing.
- To highlight ethical and regulatory considerations crucial for advancing precision pharmacotherapy.
Main Methods:
- Literature review and expert discussion on implementation barriers.
- Analysis of ethical and regulatory landscapes impacting model adoption.
Main Results:
- Several under-recognized barriers impede the practical implementation of clinical prediction models.
- Ethical and regulatory considerations are primary obstacles to widespread use.
Conclusions:
- Addressing ethical and regulatory challenges is essential for the successful integration of precision prescribing models.
- Overcoming these barriers will pave the way for the future of precision pharmacotherapy.
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