Cysteine-Containing Peptides Stimulate Monocyte Migration through NADPH-Oxidase Activation.

T L Krasnikova1, T I Arefieva2, E A Pylaeva2

  • 1Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia. tlkrasnikova@gmail.com.

Summary

Cysteine-containing peptides stimulate monocyte migration via NADPH oxidase, specifically Nox4. Apocinin and MEK/ERK blockers completely inhibited this migration, suggesting a key role for this pathway.

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