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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Related Experiment Video

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Doppler Optical Coherence Tomography of Retinal Circulation
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Published on: September 18, 2012

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Handheld optical coherence tomography angiography.

Jianlong Yang1, Liang Liu1, J Peter Campbell1

  • 1Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239, USA.

Biomedical Optics Express
|July 25, 2017
PubMed
Summary
This summary is machine-generated.

A new handheld optical coherence tomography angiography (OCTA) system was developed for real-time retinal imaging. This portable OCTA device minimizes motion artifacts, enabling clear angiograms without eye drops.

Keywords:
(110.4500) Optical coherence tomography(170.3880) Medical and biological imaging(170.4460) Ophthalmic optics and devices

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Optical coherence tomography angiography (OCTA) is crucial for visualizing retinal vasculature.
  • Existing OCTA systems are often bulky and require trained personnel for operation.
  • Minimizing motion artifacts is essential for high-quality OCTA imaging.

Purpose of the Study:

  • To develop a portable, handheld OCTA system for efficient retinal imaging.
  • To incorporate features facilitating ease of use and accurate targeting.
  • To achieve high-resolution volumetric OCTA imaging with reduced motion artifacts.

Main Methods:

  • Development of a 100-kHz swept-source laser-based handheld OCTA probe.
  • Integration of a mini iris camera, real-time en face and cross-sectional OCT display, and an electrically tunable lens for fast autofocusing.
  • Implementation of a cross-correlation-based registration algorithm for motion artifact reduction.
  • Demonstration of 2.5x2.5 mm and 3.5x3.5 mm retinal angiograms in awake adult subjects.

Main Results:

  • The handheld OCTA probe is compact (0.4 kg, 20.6 × 12.8 × 4.6 cm³) with features for easy alignment and target localization.
  • Fast automatic focusing and an extended 6 mm axial imaging range simplify operation.
  • Volumetric OCTA images were acquired with minimized motion artifacts in 1 and 2.1 seconds.
  • High-resolution retinal angiograms were successfully obtained from two awake subjects without mydriatic eye drops.

Conclusions:

  • The developed handheld OCTA system offers a portable and user-friendly solution for retinal imaging.
  • The system effectively minimizes motion artifacts, enabling rapid acquisition of high-quality volumetric retinal angiograms.
  • This technology has the potential to improve the accessibility and efficiency of OCTA examinations in clinical settings.